Leap Motion
Watch the video.
Pretty amazing stuff, though I’m still not convinced that this will upend traditional input devices in the near future.
A keyboard and mouse are far less tedious to use for long periods of time, and multitouch displays seem like they’d work better when holding a device in one hand.
There are probably a half dozen or so vertical markets, though, where this could be of particular use: Gaming, 3D design, etc.